LOCUS       NM_001368374            5188 bp    mRNA    linear   ROD 31-OCT-2023
DEFINITION  Mus musculus ring finger protein 122 (Rnf122), transcript variant
            2, mRNA.
ACCESSION   NM_001368374 XM_006509189
VERSION     NM_001368374.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5188)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5188)
  AUTHORS   Wang W, Jiang M, Liu S, Zhang S, Liu W, Ma Y, Zhang L, Zhang J and
            Cao X.
  TITLE     RNF122 suppresses antiviral type I interferon production by
            targeting RIG-I CARDs to mediate RIG-I degradation
  JOURNAL   Proc Natl Acad Sci U S A 113 (34), 9581-9586 (2016)
   PUBMED   27506794
  REMARK    GeneRIF: RNF122 suppresses antiviral type I interferon production
            by targeting RIG-I caspase activation and recruitment domains to
            mediate RIG-I degradation.
REFERENCE   3  (bases 1 to 5188)
  AUTHORS   Piao Y, Ko NT, Lim MK and Ko MS.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109163.16.
            
            On Feb 8, 2019 this sequence version replaced XM_006509189.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17784650.1326190.1,
                                           SRR13422601.157336.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-123               AC109163.16        99528-99650
            124-280             AC109163.16        102906-103062
            281-326             AC109163.16        109327-109372
            327-368             AC109163.16        109641-109682
            369-448             AC109163.16        112730-112809
            449-5188            AC109163.16        113054-117793
FEATURES             Location/Qualifiers
     source          1..5188
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 17.97 cM"
     gene            1..5188
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="ring finger protein 122"
                     /db_xref="GeneID:68867"
                     /db_xref="MGI:MGI:1916117"
     exon            1..123
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..563
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="isoform 2 is encoded by transcript variant 2; ring
                     finger protein 122 homolog"
                     /codon_start=1
                     /product="RING finger protein 122 isoform 2"
                     /protein_id="NP_001355303.1"
                     /db_xref="GeneID:68867"
                     /db_xref="MGI:MGI:1916117"
                     /translation="

MAGRRRLLAVEEGPVGPEGCFCGLGLVSTNKSCSMPPISFQDLPLNIYMVIFGTGIFVFMLSLIFCCYFISKLRNQAQSERYGYKEVVLKGDAKKLQLYGTCAVCLEDFKGKDELGVLPCQHAFHRKCLVKWLEVRCVCPMCNKPIAGPTETSQSIGILLDELV"

     misc_feature    369..506
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="RING finger, H2 subclass, found in RING finger
                     protein 122 (RNF122) and similar proteins; Region:
                     RING-H2_RNF122; cd16676"
                     /db_xref="CDD:438338"
     misc_feature    order(372..374,381..383,426..428,432..434,441..443,
                     450..452,483..485,492..494)
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:438338"
     exon            124..280
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            281..326
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            327..368
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            369..448
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            449..5188
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

aaggtacacagaagagccatggcaaatgtggggaggatgttggccctctttcagcatcagatttttctatggcaggacgaaggaggctcctggcagtagaagaaggtcctgttggtcctgaagggtgtttctgtggcctgggactggttagtaccaacaagtcctgctcaatgccaccgatcagtttccaagaccttcccctcaatatctacatggtcatcttcggcacaggcatcttcgtcttcatgcttagcctcatcttctgctgctacttcatcagcaaactccggaaccaggctcagagcgagcgatacggctacaaggaggtggtgcttaaaggtgatgctaagaagttacagctctatgggacctgtgcagtttgcctggaagacttcaaggggaaggatgaactaggcgtgcttccatgccagcatgcctttcaccgcaagtgtctggtgaagtggctagaagtacgttgtgtctgccccatgtgcaacaagcccatcgcgggccccacggagacctcgcagagcatcgggatcctgctggatgaactggtgtaagcgctcctggcacatggaccctgggaaagactgccgactttgggtacctgggtttctctacacaatgaacaagactcacacacacctaaaggcaaggatgacagagccgagcttctcccagcaccgcaggaccagtaccagacttgtccagtctccgcctcccagggcttctctccgttatccatttccaatggcctcatccaggtagactgctctatcctggcactggactgaccgtccatccagccatctccacccacctcatctttgccctgggaaggagtccactgggtgactgtgaccatgaacgcctccctttggacaacaagcgactctgaccttgaaaggctctgccccacccatgtccttcactcctgccagagctttccttgggatggtttccaagggaaaggagagaaagatcaagaaaccaagacgaaaggctctgtgtgaagtcaaggaaagcagggccctaaaaaagggaaaaatcaatgtttacatgggatgccggaaacaaaggccagcctcgccctggctgactgcagggtgatgggaccagccctcccgttaggatctgaggtgctattcattctctccctggccctgcttaatctcagagccttctagtcatcgttggtttggaagagacccctctctataggaaggggtctaatcctcaagcccattgtcaggggctttttttttttttctttttggaagcaaaacgggcctcaggctggggatggttgggaggataccatagtgcagatgtctccttcccctctgtaaatagtatttttatacttcatcttcaccatcaccatctcaggctttacacgtgcagcccctcccccacccaggatggaggggggggctgtggagtgtccccttccttccctgaacagggcggctgagagtgggaaaaggttatgtatttaaagaaaattaaatttaataacatgtttctctaatcaaatttttggcttgtggttgtggcctgtgccaggagagggaacagagctctttacctgccttcccccagtcagaccatacttgaggtttctaatccttaacaaaacctgagggctggacatctatctcaacaatagagtgcttgggtaacatgctcaaggccctgggctcagtttttggaatggaaaaaaaaaaaaaaaaagtggggagggaggattaacttattgaacactggtataaaataagatctgatgaagccaggatcaatcgttggaagttttagaaacattgtaaagttgatttcaagcacagcattcactcaactgacttgaattctacctggtggttgattgtcagtgatctggcgacctcagaggcccatgtagctaccctggcaccccatctctttactaatcctgtgtcgctgacagtccctccctggcacatcctagcctcctacacacatctagaattccatgtggtagcaacaggtatgaccctgcgtgcatccagatcctccacccacagcctccagcttagctttgccagtttcccaaggggcctgctgtcaacagtgagtgcgatcagaatgggatggtgttgggaacacctttcttaagcataaggtaactagaccctggttggcccttgcttgggagcacaaatcgatgccagtcaagcaggcagcacgccttgggtgctgagctcaggaaagccatttgctgagcatggtttggattgatgtcagctgtgaaaaagctacccatcattgagtactagatacctggagtaggtatagtgctgtcttactcagccattgtcttatgcatcttggacaacaccaaggtgtaattgggtacctgactatgggctcttctacaggaaggtgcctttactctttacattaagtgacccctgcttgctattgtcaaccttaagagaaacagatctctctccactgggtcaccacttcctcttctagcagtgatagtctggaagtattgaggaattttgatgtattttctcagccgatttcagcctacccctcagttcctgctgcaggtggattcactggtggagaaagtaatcaggttggctttgtatctcccacctcatcatctctccttgcaactgggagggttcatcagtgttagcatcctgatgaaaatgttagcacgaaaaagcttgtttcacagctttcaaaacagtgttaccaggtcaaaatgatgtgggggcaggaaataccttttattccccgtgcttctattgaacctgggtggtatatattacagagtacacagaagggaaaatgatactggttagctgatcagctcaactggcagccgctaagcacaattagacactatgtccccaattcacacagtcacctgtgaagtcttgtgacttggttaagcctttttagaacacctgctgcctggtttggccacttgacaggcaaatcctgaccttggcgaaatggtgtgagcactgtgcttgggtggcaagctcacataatcgagatctttactcagctgtcttttcagcagcagcccgagtgtatattgccaagacatgatgctcaatcagcagcccgagtgtatgccaagacatgctcagtctagggagcagtaatgtggacattgactttgattaaccagactgtggggaccagagagttcaaaccattctgtatgaactgaggtgggaaagacagtaggttagaacataaagggaggaagtactgtgtggaagccaggaacaggattggatagagtaagcaccctgaactttatttacataaaacttaaaaaaaaaaacccactatgttccatctgagaactaagcaaattattctctcctctgggtcctatatatagccacaggcagctacaatagacctataactattcaaattagcaaagaatgtataccttgaatatatctgaaagggaaaaagatcaaaggaagttgtgttgtgaccagtacatgccagcttcagcaaagaagggtttttgttctttccccccaacagaagacatttttcttgcttctctgaatatactgaatttaggattagtttgtttaaaaaaaaatcggtgctcacataattagacactaagtgtcagctaactaacacaaccccaggcagtgtggatccaaggtcagtgtcactttccttgccccacagttttgaaagcagatggtgctaaagactctcaaagtaccaggtgctgtcaagcctggtgcagtctgggaagacaagcctcatcataggcctgtgagctgtaccctagccactgttaggaacagggcagggtcttggaatttatagtctgtgtttgattacttgtttaatttggtgtctcttgtgtttaattccacaatgaatgactttttaaaaaaagatttattatttatatgtatgtatactgtacctgtcttcagacacaccagtagagggtgtcagatgtcattatggatgattgtaagccaccatgtggttgctgggatttgaactcaggaccttcagaagaacagtcggtgctcttaacctcgctgagctatatctccagctcccaatgaatgacttaagtcttaaatagaaccaccatttaaaactgggtaaatgaagtgagacagagctcctctagggaaaaatttgaaattcagcgatagcttgggataatggtgataggtgaatttaaaagtgggctaccacattgggtcacacatgcttttaatcctgacacctgagaggcagaggcaagtggatctctgaatgtgaggccagcttggtctggtctacatagatagccagggttatggggagtggggggaggtgcggggagggggagaagtcacccttcctcttgatagttctactcaaccagcacttcccatgtgttcactagaatttttattccttagttctgtcaagattgtcccttatacatgcctaccctccattctatcacattgcccgtctctttgaacatcagagtaacatcctgccaggtcactggaagctcagacttctgttgaagcctcatccacaggttcggaggggcagatgtgattgagttggagacaagaactgttattatacaaattcatgggacatgacgccatttatcatcccacttaataagcattggattccaactgatccaatccaagaaaataaaaaccatgcccatttcccttctgatgggaagacatcaaatgtcacctttgtgttttgatccgttccttatgtgacagcttaacaagaaaccatcatgtgctctgtagaggaatagctagggggacatcagccaggagatatactggaagacacttttgatggcgactgagtgttctcagtcacgaccccccacaaagctcacttttcttcctcttttttcctccaattttcttcatctattcctattctctaacattactaagatgccatactattgaagaattttccagatgggctgtaggtaccatgaatggggctctgagttctaaatgttcagtaaataagcattgagtctcaagggggtgctgatatcctcaaagacatgaatatcatttgtgatgtctggaacattaaaggaacgatgtagcataaagaagccaataaaaaccagaagaaatctctactggaa

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