LOCUS       NM_001168256            1414 bp    mRNA    linear   ROD 05-AUG-2023
DEFINITION  Mus musculus transmembrane protein 40 (Tmem40), transcript variant
            1, mRNA.
ACCESSION   NM_001168256
VERSION     NM_001168256.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1414)
  AUTHORS   Carninci P, Waki K, Shiraki T, Konno H, Shibata K, Itoh M, Aizawa
            K, Arakawa T, Ishii Y, Sasaki D, Bono H, Kondo S, Sugahara Y, Saito
            R, Osato N, Fukuda S, Sato K, Watahiki A, Hirozane-Kishikawa T,
            Nakamura M, Shibata Y, Yasunishi A, Kikuchi N, Yoshiki A, Kusakabe
            M, Gustincich S, Beisel K, Pavan W, Aidinis V, Nakagawara A, Held
            WA, Iwata H, Kono T, Nakauchi H, Lyons P, Wells C, Hume DA,
            Fagiolini M, Hensch TK, Brinkmeier M, Camper S, Hirota J, Mombaerts
            P, Muramatsu M, Okazaki Y, Kawai J and Hayashizaki Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   2  (bases 1 to 1414)
  AUTHORS   Thut CJ, Rountree RB, Hwa M and Kingsley DM.
  TITLE     A large-scale in situ screen provides molecular evidence for the
            induction of eye anterior segment structures by the developing lens
  JOURNAL   Dev Biol 231 (1), 63-76 (2001)
   PUBMED   11180952
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY279100.1, CX564997.1, CV561368.1 and AC109169.13.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a). Variants 1 and 2
            both encode isoform a.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7345562.1956156.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-101               BY279100.1         1-101
            102-853             CX564997.1         1-752
            854-974             CV561368.1         721-841
            975-1414            AC109169.13        135332-135771
FEATURES             Location/Qualifiers
     source          1..1414
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 53.68 cM"
     gene            1..1414
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /note="transmembrane protein 40"
                     /db_xref="GeneID:94346"
                     /db_xref="MGI:MGI:2137870"
     exon            1..194
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    101..103
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /note="upstream in-frame stop codon"
     exon            195..272
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..880
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /note="isoform a is encoded by transcript variant 1"
                     /codon_start=1
                     /product="transmembrane protein 40 isoform a"
                     /protein_id="NP_001161728.1"
                     /db_xref="CCDS:CCDS39601.1"
                     /db_xref="GeneID:94346"
                     /db_xref="MGI:MGI:2137870"
                     /translation="

MEASGSSSQSQDSGGVHRETEDHYQETELHKHHGKARERYKRDKSSSSSSSSSSSSSSSSSSSSSSSDSSDEDQPSRGPRKHRRRPRRDSLRGADHGELEVLKDELQLCGGAAGEMVPTGESGLRRRGSGSAEGEVEASQLRRLNIKKDDEFFHFVLLCFAIGALLVCYHYYADWFMSLGVGLLTFASLETIGIYFGLVYRIHSVLQGFIPLLQKFRLPGFRRTN"

     misc_feature    203..490
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4FJU9.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    203..205
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /note="N-acetylmethionine.
                     /evidence=ECO:0000250|UniProtKB:Q8WWA1; propagated from
                     UniProtKB/Swiss-Prot (Q4FJU9.1); acetylation site"
     misc_feature    515..874
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /note="Transmembrane protein 40 family; Region: TMEM40;
                     pfam15817"
                     /db_xref="CDD:374141"
     misc_feature    587..589
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:21183079; propagated from
                     UniProtKB/Swiss-Prot (Q4FJU9.1); phosphorylation site"
     misc_feature    656..718
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4FJU9.1);
                     transmembrane region"
     misc_feature    737..799
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /note="propagated from UniProtKB/Swiss-Prot (Q4FJU9.1);
                     transmembrane region"
     exon            273..404
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            405..479
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            480..533
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            534..569
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            570..602
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            603..650
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            651..722
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            723..797
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            798..860
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            861..1414
                     /gene="Tmem40"
                     /gene_synonym="9030407H20Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ttcgctgctgtgaatagacaagggaatggctattcagcactttcagagagtggccggtggacacagaaactatctgcccaccacgagctgacagaggatctgactcctcctatcaactctgcagcgagggcaagagcaagcagaaagcaggccagaggcatggactgacatctcaccaagagaaaggaaaggagggaaagtcatggaggcttcaggatcttcttcccagtctcaagacagtggtggagtccacagggaaacggaagatcactaccaagagacagagctccacaagcatcatgggaaggcccgggagcgatataagagagacaagtcttcctcttcatcctcatcctcgtcatcttcttcctcctcttcctcctcatcttcttcctcctcctcagacagcagcgatgaggaccagccctccagaggtcccaggaaacacagaaggaggccccgcagggacagcttgcgtggtgccgaccatggggaactggaagtgctaaaggacgagcttcagctctgcggaggtgctgctggggaaatggtgcctactggggagtcaggactccgaaggagaggttccggctcagcggagggagaagtggaggcctctcagttaagaagactgaacataaagaaggatgatgagtttttccattttgtccttctctgctttgccatcggagccttgctggtgtgttaccactactatgcagactggttcatgtccctcggggtcggcctgctcacctttgcttctctcgagaccattggcatctatttcgggctcgtgtaccggatccacagcgtgcttcagggcttcatccccctccttcagaagttccggctgccagggttcaggagaactaactgagatcactgcctgacagcagctgagccagtccccaatgtgaccactgtaaccactgccatgcctgagcccagaagacagaacgacgcgctggaagacaccagaaggccacacaataaagagctctttccttccacgtgatctgagtgtcggcaccagtgggcaggctcttgctctgcagattaacacgcagtctccgtggggaagagaagaggggatagcgtcgggtcagcacggaggagctgggatgccattgctcataggtcaacatgaatcctgggttctgcaggctggcatctgcgggcctgggtctctctggtgtcctcaggccatgcccaggagctcacagttcctgcagagccttcttgggacagccattctgaggcagggagctaccaggctgggttcccaggggaacttgttgcaggtaagacgctggggaccaaagctgcggacccatcatagctgaccaaccctgttgcccttggactcctaaaatccaaataaattttctgttccttgtgcttaaaaaaaaaa

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